KLK3 and cancer: We showed that SBx with the predictor PSA is a better discriminator of high cancers and not high cancers, with the area under the ROC curve 87.5%, the sensitivity, 83.3% and the specificity, 83.8%, than the one just based on SBx alone (Cohen’s Kappa = 0.34, sensitivity = 73.3% and specificity = 87.3%).