EGFR and cancer: Survival meta-analysis showed that NUAK1, Akt isoforms (Akt1, Akt2, and Akt3), mTOR, and Rictor positively correlate with a high hazard ratio (HR) in BRCA, COAD, GBM, PRAD, STAD, and OV (Fig. 9L), the same types of cancer where NUAK1 correlates with EGFR expression and Akt Ser-473 phosphorylation.