Within this pathway, we identified several proteins associated with the modulation of anxiety-related behaviors, such as Cortistatin [43], Neuronal Nicotinic Acetylcholine Receptor [44], Opioid-Related Nociceptin Receptor 1 [45], Tachykinin Receptor 3 [21], Somatostatin receptor 1 [46], Tachykinin Precursor 1 [47] and Neurotensin [48]. The gene discussed is SSTR1; the disease is Anxiety.