In the acute phase, when compared to controls, we also observed increases in a range of inflammatory mediators (IL-6, HGF, IL-12p40, IL-1RA, CCL2, and M-CSF) in the overall cohort of COVID-19 participants, with HGF and IL-12p40 showing robust differentiation between participants with and without alterations in consciousness. This evidence concerns the gene IL6 and COVID-19.