Inhibition of BRD4 with the BRD4 inhibitor JQ1 or OTX015 abolishes PAX3-FOXO1 function, suppresses alveolar rhabdomyosarcoma cell proliferation in vitro and induces tumor growth inhibition in mouse models [39] (Table 1). The gene discussed is FOXO1; the disease is alveolar rhabdomyosarcoma.