RECQL deficient tumors with PD1+ T-cell infiltration (Table 4) were significantly associated with high grade, de-differentiation, pleomorphism, higher mitotic index, high Ki67 expression, high risk Nottingham prognostic index (NPI), ER-, PR- and triple negative breast cancers (all p values ≤0.0001) compared to RECQL proficient FOXP3- tumors. The gene discussed is FOXP3; the disease is triple-negative breast carcinoma.