Breast cancer specific survival (BCSS) was significantly shorter in RECQL deficient tumors with CD8+ T-cell infiltration within tumor cell nests (Fig. 2I, (p < 0.0001; HR = 0.87; 95 % CI =0.77-0.99), adjacent stroma (Supplementary Fig. 1A, p =0.038; HR = 0.87; 95 % CI =0.76-1.13), distant stroma (Supplementary Fig. 1B, p= 0.006; HR = 0.73; 95 % CI =0.59-0.90), and total CD8+ T-cell infiltration (Supplementary Fig. 1C, p = 0.04; HR = 0.86; 95 % CI =0.73-1.1) compared to RECQL proficient CD8- tumors. Here, CD8A is linked to breast cancer.