RECQL deficient tumors with tumor cell PDL1 expression (PDL1+) (Table 3) were significantly associated with high grade, pleomorphism, higher mitotic index, high Ki67 expression, lymph node positivity and high-risk Nottingham prognostic index (NPI) (all p values ≤0.001) compared to RECQL proficient PDL1- tumors. The gene discussed is MKI67; the disease is neoplasm.