Previously, we have shown that low RECQL breast tumors were significantly associated with low PARP1, BRCA1 negative, low RAD51, low ATM, low nuclear pChk1, low nuclear Chk2, low XRCC1, low FEN1, low SMUG1, and low DNA-PKcs expression [6] . The gene discussed is PRKDC; the disease is breast neoplasm.