FBXO3 and breast cancer: Our results showed that while ectopic expression of FBXO3 significantly promoted cell migration in MCF-10A cells, a cell line predominantly expressing ΔNp63α, FBXO3 could also significantly increase cell migration of breast cancer cells in which the expression of ΔNp63α protein were undetectable, including MDA-MB-231, MDA-MB-468, SKBR3, or Hs578T cells (Figs 1A–1C and S1A).