As increased of ROS and DNA damage could also induce necroptosis, ferroptosis, and autophagic cell death [43–45], we next treated NeuroD1-knocked down HCC-LM3 cells with other three inhibitors, necroptosis inhibitor necrosulfonamide (NSA), ferroptosis inhibitor ferrostatin-1 (Ferr-1), and autophagic cell death inhibitor 3-methyladenine (3-MA). Here, NEUROD1 is linked to hepatocellular carcinoma.