Upregulation of genes involved in ferroptosis resistance, such as solute carrier family 7 member 11 (SLC7A11) and glutathione peroxidase 4 (GPX4), as well as downregulation of polyunsaturated fatty acid (PUFA)-containing PLs (PUFA-PLs), which are key catalytic enzyme substrates in ferroptosis, have been linked to ferroptosis evasion and enhanced tumor growth [30, 31]. The gene discussed is SLC7A11; the disease is neoplasm.