Dobrowolski et al examined the types of p14 expression in tissue samples from benign melanocytic nevi, primary melanomas and melanoma metastases and detected a notable inverse association between the intensity of p14 immunohistochemical staining and the evolution of cutaneous melanocytic tumoral populations.[21] The interpretation stemmed from the observation of p14 overexpression in almost all of the benign nevi, in comparison with its absence in 3⁄4 of primary melanomas and in all melanoma metastases.[17]. Here, CDKN2A is linked to melanoma.