The diagnostic journey for patients with MYH9-RDs can be challenging due to overlapping features with other thrombocytopenic disorders, particularly immune thrombocytopenia (ITP).[3] Misdiagnosis of MYH9-RDs as ITP is common, leading to inappropriate treatments and delayed identification of the underlying condition. Here, MYH9 is linked to autoimmune thrombocytopenic purpura.