NR3C1 and HIV infectious disease: Of particular relevance to side-effects mediated via the GR, we previously showed that unlike for NET, MPA increases HIV infection in PBMCs at 50 nM but not at 10 nM ex vivo [51] and increases HIV replication at 10 nM and 100 nM in endocervical explants, but only at 100 nM, and not at 10 nM, in ectocervical tissue explants [50], while others have detected significant effects of MPA on female genital tract primary cells ex vivo with 1 nM MPA [55].