ADAR editing has been implicated in the development and progression of multiple neurological, neurodegenerative and psychiatric disorders such as epilepsy [61–64], autism [65, 66], schizophrenia [67], Amyotrophic Lateral Sclerosis (ALS) [68–71], Huntington’s Disease (HD) [67], Alzheimer’s Disease (AD) [67, 72–74], schizophrenia [75–80], suicide [75, 77, 78, 80], and depression [81, 82]. Here, ADAR is linked to Alzheimer disease.