Interleukin-17 (IL-17) acts in host defense and is involved in inflammatory, autoimmune, metabolic, and neoplastic disorders 6,7., Although studies have hypothesized over the years that SNPs may alter the production of interleukins in the relationship between microbial factors and heredity, in the presence of AP, 3,7,8,9,10 the mechanisms, genetic influence, and clinical outcomes remain poorly elucidated 11,.12 The gene discussed is IL17A; the disease is neoplastic disease or syndrome.