Whilst the performance of the lateral flow tests was similar to the sensitivities and specificities reported in other studies, only four (13%) assays (Zheihang Orient Gene COVID-19 IgG/IgM, Genrui Novel Coronavirus (2019-nCoV) IgG/IgM, Biosynex COVID-19 BSS IgG/IgM, Boson Biotech 2019-nCoV IgG/IgM) were recommended for South Africa Health Products Regulatory Authority (SAHPRA) approval [25]. The gene discussed is CD40LG; the disease is COVID-19.