In the animal model of vincristine-induced peripheral neuropathy, several concentrations of biomarkers were strongly (LIX, MCP-1, NfL, and VEGF) to moderately (fractalkine, MIP-1α, and RANTES) correlated with tactile allodynia thresholds, whereas for the bortezomib model, only LIX concentrations were moderately correlated with tactile allodynia thresholds, and no such correlations were reported for oxaliplatin and paclitaxel. The gene discussed is CX3CL1; the disease is peripheral neuropathy.