These findings were in accordance with Long et al. [18], who demonstrated a significant reduction in testicular expression of vascular endothelial growth factor (VEGF) in animals with type 2 diabetes, which induces impairment of testicular microcirculation, via reduction in vascular area and blood velocity in the testis, leading to testicular histological and functional disorders. Here, VEGFA is linked to type 2 diabetes mellitus.