Meroterpenoids isolated from Sargassum serratifolium (Phaeophyceae), like sargahydroquinoic acid, sargachromenol and sargaquinoic acid, also decrease melanogenesis in melanoma cells activated by α-MSH (α-melanocyte-stimulating hormone), influencing CREB signaling pathways [16]. Here, CREB1 is linked to melanoma.