MTOR and urinary bladder cancer: Isolated from the soft coral Cladiella kashmani, flaccidoxide-13-acetate inhibited the cell migration and invasion of T24 and RT4 bladder cancer cells (1–10 μM), which were associated with a reduction in p-PI3K, p-AKT, and p-mTOR proteins (2.5–10 μM) [34].