AKT1 and hepatocellular carcinoma: Also, flaccidoxide-13-acetate reduced the cellular viability (8 μM, 24 h) and the migration/invasion (4–8 μM, 24 h) of HA22T and HepG2 hepatocellular carcinoma cells [33]; these cellular responses were accompanied by reduced protein levels of p-PI3K, p-AKT, and p-mTOR [33].