CHUK and type 2 diabetes mellitus: The results showed that the expression levels of TMEM173 (Transmembrane Protein 173), CHUK (Conserved Helix-loop-helix Ubiquitous Kinase), and the miRNAs miR-611, miR-5192, and miR-1976 gradually increased from the control group to the prediabetes group and reached their highest levels in the type-2 diabetes group, while the expression of lncRNAs RP4-60503.4 and AC074117.2 gradually decreased from the control group to the prediabetes group and reached their lowest levels in the type-2 diabetes group [55].