ACE2 and COVID-19: Moreover, the steroid derivative compounds in the T. cylindrica lipophilic extracts, known as estra-1,3,5(10)-trien-17-β-ol-17-α-butadinyl-3-methoxy;17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta(a)phenanthrene-3-ol, and stigmasta-5,24(28)-dien-3-ol,(3β,24Z)-, were able to inhibit the DM and COVID-19-related protein targets, namely α-glucosidase, α-amylase, ACE2, and TMRPSS2.