To eliminate intracellular fungi, Th1 and Th17 immune responses must be activated since IFN-γ will activate macrophages to a fungicidal state, and IL-17 plays an important role in facilitating neutrophil infiltration and the production of antifungal peptides [40,41], which are associated with resistance to fungal infection [42,43,44,45,46,47]. The gene discussed is IL17A; the disease is fungal infectious disease.