Furthermore, a significant difference was found in serum visfatin level between the groups of obese participants with periodontitis and systematic healthy participants without periodontal diseases A higher level of serum visfatin was found in the OP group than NnP (Figure 5, MD = 13.02; 95% CI: 7.34–18.70, p < 0.00001) [28,30,33]. The gene discussed is NAMPT; the disease is periodontal disorder.