HIF1A and breast cancer: It targets proteasome maturation protein (POMP), stathmin (Stmn1), and DNA (cytosine-5)-methyltransferase 3A (DNMT3A), which suppress the proliferation of BC cells by decreasing the expression levels of Jak2, EYA1, and SOX2 and by reducing levels of VHL, which negatively regulates hypoxia-inducible factor 1-alpha (HIF1alpha), leading to the apoptosis of cancer cells [115].