CRP and Sepsis: The reduction in the inflammation impact associated with post-traumatic sepsis or bacterial colonization via a specific antimicrobial therapy failed in all of the patients treated before ozone therapy as a result of continuous relapses in inflammation events and a modest reduction in the major biomarkers (CRP = −16.16%, p = 0.00512; ESR = −10.54%, p = 0.0053) due to MRB (Table 1).