Levels of proteins Rngtt, Rp1l1, Tacstd2, Zfyve26, and Zfyve27, which are known to promote a proliferative phenotype in various cancers, were decreased in the brain vasculature of TGF mice, likely as an attempt to attenuate vascular proliferation and remodeling. This evidence concerns the gene ZFYVE26 and cancer.