UBE2S and hydrops fetalis: With regard to the functional annotation clustering, the Crossbred-HF comparison revealed some interesting GO terms like ubiquitin protein ligase activity (GO:0061630), protein kinase binding (GO:0019901), protein ubiquitination (GO:0016567), innate immune response (GO:0045087) and positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123).