According to a recent study, exosomal circSHKBP1 is upregulated in GC patients and promotes GC cell proliferation, migration, and invasion by acting as a sponge for miR-582-3p, which upregulates vascular endothelial growth factor (VEGF) and Hu-antigen R (HUR) while inhibiting the degradation of heat shock protein 90 (HSP90). This evidence concerns the gene VEGFA and gastric cancer.