Other factors, such as female gender [19,20], T1D [16,17], age > 65 years old [18,19], a high BMI [17,21,22,23], hypoalbuminemia [24,25], poor nutritional status [19,20,21,22,23,24], low levels of physical activity [19,22,24,25,26], and high insulin requirements [27], are risk factors for the development of sarcopenia, which was independently associated with short-term mortality after hospital discharge [28]. The gene discussed is INS; the disease is sarcopenia.