Zetterberg and Burnham also focused on the blood-based biomarkers for AD, such as plasma Aβ, plasma tau, plasma neurofilament light, and panels of biomarkers (i.e., protein biomarkers panel, panels of blood-based biomarker-associated disease phenotypes, metabolomics, miRNA biomarker panels, exosomes, etc.)[112]. Here, MAPT is linked to Alzheimer disease.