Volcano plot showed significantly upregulated transcripts of transmembrane 4 L6 family member 1 (TM4SF1), neuritin 1 (NRN1), MT2, mucin‐like protein 3 (MUCL3), complement component 4B (C4B) and insulin‐like growth factor‐binding protein 4 (IGFBP4) genes in treated KPC mice cancer cells. The gene discussed is IGFBP4; the disease is cancer.