Out of 96 CAM genes, nine genes including claudin (CLDN‐3, ‐4, ‐6, ‐7), myelin protein zero like 1 (MPZL1), cell adhesion molecule 1 (CADM1), cadherin 3 (CDH3), activated leukocyte cell adhesion molecule (ALCAM) and integrin alpha‐6 (ITGA6) were significantly modulated in the cancer cells of treated tumours. The gene discussed is CALM3; the disease is cancer.