NFKB1 and cancer: The GSEA analysis results of BIRC3 observed that various cancer-promoting pathways were enriched in the high expression group including IL2 STAT5 signaling, IL6-JAK-STAT3 signaling, KRAS signaling, PI3K-AKT-MTOR signaling and TNFA signaling via NFKB (Fig. 7F).