Another pathological characteristic of AD patients is the hyperphosphorylation of tau proteins in the brain, leading to excessive deposition of some amyloid proteins in the brain tissue, leading to the development of specific senile plaques and causing some neuronal tangles leading to neuronal damage and further affecting the function of the neuronal system in the patient’s brain (Wu et al., 2021). The gene discussed is MAPT; the disease is Alzheimer disease.