The mechanisms involved in the preventive action of aspirin on GCA-induced stroke are not clearly understood: prevention of embolization from artery to artery (in keeping with the efficiency of warfarin), or the preventive effect of aspirin on intimal hyperplasia via the NF-κB pathway (156), like the action of steroids, or the repression of IFNγ transcription (with no effect on the transcription of IL1β and IL6). The gene discussed is IL1B; the disease is temporal arteritis.