Tissue Resident B Cells Form Tertiary Lymphoid Structures (TLS), Which Are Associated With Improved Survival And Response To Immune Checkpoint Blockade In NSCLC Patients. Til-B Can Act As A Local Apc To Secondary Stimulate CD4+ Til In Non-Small Cell Lung Cancer, Ultimately Altering Its Phenotype And Function. This evidence concerns the gene CD4 and non-small cell lung carcinoma.