We observed increased expression in oBM-MSC for GAL-1, a lectin which has been associated to nuclear factor kappaB (NF-kB) pathway activation and cancer progression, IL-6, a strong activator of acute phase response, IL-8, a chemokine with a specific affinity for neutrophils, TGF-β, a potent inducer of chemotaxis which is able to enhance T-cells activity and TSG-6, a marker of many autoimmune and chronic inflammatory disorders (61–66). The gene discussed is TNFAIP6; the disease is cancer.