Through validation using a mouse model of ALI, a final selection of 10 genes (Ptprc, Cd14, Clec4n, Ms4a6d, Cxcl10, Cd44, Lilrb4, Cxcl1, Bcl2a1b, and Slc15a3) was confirmed to be significantly associated with ALI. This evidence concerns the gene CLEC6A and acute respiratory distress syndrome.