Through validation using a mouse model of ALI, a final selection of 10 genes (Ptprc, Cd14, Clec4n, Ms4a6d, Cxcl10, Cd44, Lilrb4, Cxcl1, Bcl2a1b, and Slc15a3) was confirmed to be significantly associated with ALI. The gene discussed is CXCL10; the disease is acute respiratory distress syndrome.