Others such as anti-TIGIT or anti-TIM-3, as well as new combinations of ICIs, are being explored to potentiate anti-tumor immune response in different cancer types including solid tumors, multiple myeloma, endometrial cancer, and gastric cancer, among others (NCT02913313, NCT03119428, NCT02817633, NCT03099109, NCT02608268, NCT01968109). Here, TIGIT is linked to neoplasm.