Degradation of GPX4 protein by CMA seems to be a common response to various ferroptosis activators.[74–76] Moreover, CMA-induced ferroptosis can be observed in inflammatory models caused by different injury factors, such as aseptic inflammation caused by pancreatitis,[77] radiation,[78] and ischemia-reperfusion,[79] and infection we mentioned above[39, 40]. The gene discussed is GPX4; the disease is infection.