ETNK1 and testicular germ cell tumor: Moreover, it has been reported that overexpression of genes from 12p11.2 to 12p12.1 is a feature of all TGCTs and the overexpression of genes from this region, particularly in non-seminomas and seminomas with amplification, might play a key role in driving TGCT progression.[30] In our study, STRAP (chr12:15), INTS13 (chr12:26), and ETNK1 (chr12:22) were the most genetic alteration-related genes for GOLT1B (chr12:21), and were all located at 12p15-26, with amplification as the primary genetic alteration type.