A review of the clinical, laboratory, imaging, and pathologic findings (Table 1) in our patients with the GCM2 p.Tyr394Ser variant showed that all patients had asymptomatic disease and mild (patients 1 and 3) or moderate (patient 2) hypercalcemia (Table 1), with mild to moderate elevated PTH. The gene discussed is GCM2; the disease is hypercalcemia disease.