C4BPA and coronary artery disorder: We found two significant associations between proteins and the PRS of CAD: C4b-binding protein alpha chain (protein ID: P04003; nominal p-value = 6.0E − 04; Bonferroni p-value = 4.0E − 02) and Apolipoprotein B-100 (protein ID: P04114; nominal p-value = 5.2E − 04; Bonferroni p-value = 3.4E − 02).