The pathways that were enriched for HS time-period 3 were mainly related to signaling (i.e., oxytocin signaling pathway, mTOR signaling pathway, and hippo signaling pathway), cardiac disease (i.e., hypertrophic cardiomyopathy, dilated cardiomyopathy), and hormone synthesis and regulation (i.e., aldosterone synthesis and secretion). Here, MTOR is linked to dilated cardiomyopathy.