Furthermore, in Head and Neck squamous cell carcinoma (HNSC), LIPT2 expression showed a positive correlation with regulatory T cells (Tregs) and macrophage infiltration, and in Uveal Melanoma (UVM), it exhibited a positive correlation with monocyte, neutrophil, and CD8+ T cell infiltration, but negatively correlated with Tregs and dendritic cell (DC) infiltration in THCA. Here, LIPT2 is linked to head and neck squamous cell carcinoma.