Western Blot (Supplementary Material 1) and qRT-PCR revealed a noteworthy rise in protein expression (Fig. 8A–D) and mRNA expression (Fig. 8E–H) of ASNS, GPT2, RRM2, and NFE2L2 in DU-145 PCa cell line in comparison to RWPE-1 normal PCa cell line. This evidence concerns the gene RRM2 and posterior cortical atrophy.