Average Th mRNA levels in untreated HD mice were upregulated by N-PPG to 40 % of control WT levels, average Drd1 levels were upregulated to 44 %, and average Adora2a levels were upregulated to 32 % of control WT brain levels with the N-PPG treatment (Suppl. The gene discussed is TH; the disease is Huntington disease.