Dengue-specific CD8+ T cells, D-dext+CD8+, were detected using four HLA-A∗0201, one HLA-A∗0301, and three HLA-B∗0702 dengue dextramers in 19 participants carrying the corresponding HLA alleles (eight LD, eight HD, and three vehicle-GNP), at days 0, 35 and 180. This evidence concerns the gene CD8A and dengue disease.