S1 Table shows the number and percentage of missing data. The missing data were addressed by multiple imputation, and there was no significant difference before and after imputation (S1 Fig). The characteristics of included patients were shown in Table 1. There was statistical significance in race, duration of diabetes, smoking, BMI, anti-diabetic agent, CKD, anemia, WBC, MPV, ALB, FBG, GHb, RAR, and all-cause mortality between mild level group and moderate/severe level group (all P < 0.05). This evidence concerns the gene ALB and chronic kidney disease.