ATOX1 and neoplasm: Only in 2015, a group of scientists from the Department of Hematology and Medical Oncology at Emory University showed that inhibition of Atox1 directly reduces the proliferation of tumor cells [32], and the binding of Atox1 to the cis-element of Cyclin D1 stimulates the growth and proliferation of mouse embryonic fibroblasts, as well as SW480 and SW620 colorectal cancer cells [33, 34].