BMP8B and metabolic dysfunction-associated steatohepatitis: Similarly, a significant positive correlation exists between serum BMP8B levels and aspartate aminotransferase (AST) (r = 0.31, p = 0.005), alanine aminotransferase (ALT) (r = 0.23, p = 0.045), APRI (r = 0.30, p = 0.009), Fib-4 score (r = 0.25, p = 0.036) in NASH patients (Fig 4) (S2 Fig).