BDNF and myalgic encephalomeyelitis/chronic fatigue syndrome: Polli et al. [46] performed a repeated-measure regression model showing that serum BDNF predicts chronic fatigue syndrome (CFS) symptoms list scores (F = 14.410, t = 3.796, 95% CI = 1.79 to 5.71, p-value = 0.001) and widespread hyperalgesia (F = 4.147, t = 2.036, 95% CI = 0.01 to 0.08, p-value = 0.044).